Cargando…

Keratin Profiling by Single-Cell RNA-Sequencing Identifies Human Prostate Stem Cell Lineage Hierarchy and Cancer Stem-Like Cells

Single prostate stem cells can generate stem and progenitor cells to form prostaspheres in 3D culture. Using a prostasphere-based label retention assay, we recently identified keratin 13 (KRT13)-enriched prostate stem cells at single-cell resolution, distinguishing them from daughter progenitors. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Wen-Yang, Hu, Dan-Ping, Xie, Lishi, Nonn, Larisa, Lu, Ranli, Abern, Michael, Shioda, Toshihiro, Prins, Gail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346986/
https://www.ncbi.nlm.nih.gov/pubmed/34360875
http://dx.doi.org/10.3390/ijms22158109