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Signaling Pathways Regulated by UBR Box-Containing E3 Ligases

UBR box E3 ligases, also called N-recognins, are integral components of the N-degron pathway. Representative N-recognins include UBR1, UBR2, UBR4, and UBR5, and they bind destabilizing N-terminal residues, termed N-degrons. Understanding the molecular bases of their substrate recognition and the bio...

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Detalles Bibliográficos
Autores principales: Kim, Jung Gi, Shin, Ho-Chul, Seo, Taewook, Nawale, Laxman, Han, Goeun, Kim, Bo Yeon, Kim, Seung Jun, Cha-Molstad, Hyunjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346999/
https://www.ncbi.nlm.nih.gov/pubmed/34361089
http://dx.doi.org/10.3390/ijms22158323