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The Impact of Epigenetic Modifications on Adaptive Resistance Evolution in Glioblastoma

Glioblastoma (GBM) is a highly lethal cancer that is universally refractory to the standard multimodal therapies of surgical resection, radiation, and chemotherapy treatment. Temozolomide (TMZ) is currently the best chemotherapy agent for GBM, but the durability of response is epigenetically depende...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Berglund, Anders E., Etame, Arnold B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347012/
https://www.ncbi.nlm.nih.gov/pubmed/34361090
http://dx.doi.org/10.3390/ijms22158324