Reduced Endothelin-2 and Hypoxic Signaling Pathways in Granulosa-Lutein Cells of PCOS Women

Granulosa-lutein cells (GLCs) from PCOS women display reduced HIF-1α and EDN2 levels, suggesting their role in PCOS etiology. Here, we investigated the mechanisms involved in aberrant EDN2 expression in PCOS, and its association with HIF-1α. Various HIF-1α-dependent factors were studied in GLCs from...

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Detalles Bibliográficos
Autores principales: Szymanska, Magdalena, Shrestha, Ketan, Girsh, Eliezer, Harlev, Avi, Eisenberg, Iris, Imbar, Tal, Meidan, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347025/
https://www.ncbi.nlm.nih.gov/pubmed/34360981
http://dx.doi.org/10.3390/ijms22158216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347025/
https://www.ncbi.nlm.nih.gov/pubmed/34360981
http://dx.doi.org/10.3390/ijms22158216

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