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Simulations of Promising Indolizidine—α6-β2 Nicotinic Acetylcholine Receptor Complexes

Smoking-cessation drugs bind many off-target nicotinic acetylcholine receptors (nAChRs) and cause severe side effects if they are based on nicotine. New drugs that bind only those receptors, such as [Formula: see text] 6 [Formula: see text] 2* nAChR, implicated in nicotine addiction would avoid the...

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Detalles Bibliográficos
Autores principales: Acquah, Francis A., Paramel, Matthew, Kuta, Adama, Hussaini, Syed R., Wallace, David R., Mooers, Blaine H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347036/
https://www.ncbi.nlm.nih.gov/pubmed/34360698
http://dx.doi.org/10.3390/ijms22157934