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Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

The purpose of this work is to investigate the protein kinase inhibitory activity of constituents from Acacia auriculiformis stem bark. Column chromatography and NMR spectroscopy were used to purify and characterize betulin from an ethyl acetate soluble fraction of acacia bark. Betulin, a known indu...

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Detalles Bibliográficos
Autores principales: Ahmadu, Augustine A., Delehouzé, Claire, Haruna, Anas, Mustapha, Lukman, Lawal, Bilqis A., Udobre, Aniefiok, Baratte, Blandine, Triscornia, Camilla, Autret, Axelle, Robert, Thomas, Bulinski, Jeannette Chloë, Rousselot, Morgane, Simoes Eugénio, Mélanie, Dimanche-Boitrel, Marie-Thérèse, Petzer, Jacobus P., Legoabe, Lesetja J., Bach, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347092/
https://www.ncbi.nlm.nih.gov/pubmed/34361750
http://dx.doi.org/10.3390/molecules26154599