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Mouse Models of Achromatopsia in Addressing Temporal “Point of No Return” in Gene-Therapy

Achromatopsia is characterized by amblyopia, photophobia, nystagmus, and color blindness. Previous animal models of achromatopsia have shown promising results using gene augmentation to restore cone function. However, the optimal therapeutic window to elicit recovery remains unknown. Here, we attemp...

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Detalles Bibliográficos
Autores principales: Wang, Nan-Kai, Liu, Pei-Kang, Kong, Yang, Levi, Sarah R., Huang, Wan-Chun, Hsu, Chun-Wei, Wang, Hung-Hsi, Chen, Nelson, Tseng, Yun-Ju, Quinn, Peter M. J., Tai, Ming-Hong, Lin, Chyuan-Sheng, Tsang, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347118/
https://www.ncbi.nlm.nih.gov/pubmed/34360834
http://dx.doi.org/10.3390/ijms22158069