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Mouse Models of Achromatopsia in Addressing Temporal “Point of No Return” in Gene-Therapy
Achromatopsia is characterized by amblyopia, photophobia, nystagmus, and color blindness. Previous animal models of achromatopsia have shown promising results using gene augmentation to restore cone function. However, the optimal therapeutic window to elicit recovery remains unknown. Here, we attemp...
Autores principales: | Wang, Nan-Kai, Liu, Pei-Kang, Kong, Yang, Levi, Sarah R., Huang, Wan-Chun, Hsu, Chun-Wei, Wang, Hung-Hsi, Chen, Nelson, Tseng, Yun-Ju, Quinn, Peter M. J., Tai, Ming-Hong, Lin, Chyuan-Sheng, Tsang, Stephen H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347118/ https://www.ncbi.nlm.nih.gov/pubmed/34360834 http://dx.doi.org/10.3390/ijms22158069 |
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