Inhibition of Cardiac RIP3 Mitigates Early Reperfusion Injury and Calcium-Induced Mitochondrial Swelling without Altering Necroptotic Signalling

Receptor-interacting protein kinase 3 (RIP3) is a convergence point of multiple signalling pathways, including necroptosis, inflammation and oxidative stress; however, it is completely unknown whether it underlies acute myocardial ischemia/reperfusion (I/R) injury. Langendorff-perfused rat hearts su...

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Detalles Bibliográficos
Autores principales: Horvath, Csaba, Young, Megan, Jarabicova, Izabela, Kindernay, Lucia, Ferenczyova, Kristina, Ravingerova, Tanya, Lewis, Martin, Suleiman, M. Saadeh, Adameova, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347133/
https://www.ncbi.nlm.nih.gov/pubmed/34360749
http://dx.doi.org/10.3390/ijms22157983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347133/
https://www.ncbi.nlm.nih.gov/pubmed/34360749
http://dx.doi.org/10.3390/ijms22157983

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