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Inhibition of Cardiac RIP3 Mitigates Early Reperfusion Injury and Calcium-Induced Mitochondrial Swelling without Altering Necroptotic Signalling
Receptor-interacting protein kinase 3 (RIP3) is a convergence point of multiple signalling pathways, including necroptosis, inflammation and oxidative stress; however, it is completely unknown whether it underlies acute myocardial ischemia/reperfusion (I/R) injury. Langendorff-perfused rat hearts su...
Autores principales: | Horvath, Csaba, Young, Megan, Jarabicova, Izabela, Kindernay, Lucia, Ferenczyova, Kristina, Ravingerova, Tanya, Lewis, Martin, Suleiman, M. Saadeh, Adameova, Adriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347133/ https://www.ncbi.nlm.nih.gov/pubmed/34360749 http://dx.doi.org/10.3390/ijms22157983 |
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