Novel High Affinity Sigma-1 Receptor Ligands from Minimal Ensemble Docking-Based Virtual Screening

Sigma-1 receptor (S1R) is an intracellular, multi-functional, ligand operated protein that also acts as a chaperone. It is considered as a pluripotent drug target in several pathologies. The publication of agonist and antagonist bound receptor structures has paved the way for receptor-based in silic...

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Detalles Bibliográficos
Autores principales: Dvorácskó, Szabolcs, Lázár, László, Fülöp, Ferenc, Palkó, Márta, Zalán, Zita, Penke, Botond, Fülöp, Lívia, Tömböly, Csaba, Bogár, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347176/
https://www.ncbi.nlm.nih.gov/pubmed/34360878
http://dx.doi.org/10.3390/ijms22158112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347176/
https://www.ncbi.nlm.nih.gov/pubmed/34360878
http://dx.doi.org/10.3390/ijms22158112

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