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Heme Oxygenase-1 Induction by Cobalt Protoporphyrin Ameliorates Cholestatic Liver Disease in a Xenobiotic-Induced Murine Model

Cholestatic liver diseases can progress to end-stage liver disease and reduce patients’ quality of life. Although their underlying mechanisms are still incompletely elucidated, oxidative stress is considered to be a key contributor to these diseases. Heme oxygenase-1 (HO-1) is a cytoprotective enzym...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Yeon, Choi, Yongmin, Leem, Jaechan, Song, Jeong Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347179/
https://www.ncbi.nlm.nih.gov/pubmed/34361019
http://dx.doi.org/10.3390/ijms22158253