Cargando…

Identification of Broad-Spectrum MMP Inhibitors by Virtual Screening

Matrix metalloproteinases (MMPs) are the family of proteases that are mainly responsible for degrading extracellular matrix (ECM) components. In the skin, the overexpression of MMPs as a result of ultraviolet radiation triggers an imbalance in the ECM turnover in a process called photoaging, which u...

Descripción completa

Detalles Bibliográficos
Autores principales: Gimeno, Aleix, Cuffaro, Doretta, Nuti, Elisa, Ojeda-Montes, María José, Beltrán-Debón, Raúl, Mulero, Miquel, Rossello, Armando, Pujadas, Gerard, Garcia-Vallvé, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347235/
https://www.ncbi.nlm.nih.gov/pubmed/34361703
http://dx.doi.org/10.3390/molecules26154553