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Identification of Broad-Spectrum MMP Inhibitors by Virtual Screening
Matrix metalloproteinases (MMPs) are the family of proteases that are mainly responsible for degrading extracellular matrix (ECM) components. In the skin, the overexpression of MMPs as a result of ultraviolet radiation triggers an imbalance in the ECM turnover in a process called photoaging, which u...
Autores principales: | Gimeno, Aleix, Cuffaro, Doretta, Nuti, Elisa, Ojeda-Montes, María José, Beltrán-Debón, Raúl, Mulero, Miquel, Rossello, Armando, Pujadas, Gerard, Garcia-Vallvé, Santiago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347235/ https://www.ncbi.nlm.nih.gov/pubmed/34361703 http://dx.doi.org/10.3390/molecules26154553 |
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