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3D-Printed Gelatin Methacrylate Scaffolds with Controlled Architecture and Stiffness Modulate the Fibroblast Phenotype towards Dermal Regeneration

Impaired skin wound healing due to severe injury often leads to dysfunctional scar tissue formation as a result of excessive and persistent myofibroblast activation, characterised by the increased expression of α-smooth muscle actin (αSMA) and extracellular matrix (ECM) proteins. Yet, despite extens...

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Detalles Bibliográficos
Autores principales: R. Ibañez, Rita I., do Amaral, Ronaldo J. F. C., Reis, Rui L., Marques, Alexandra P., Murphy, Ciara M., O’Brien, Fergal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347286/
https://www.ncbi.nlm.nih.gov/pubmed/34372114
http://dx.doi.org/10.3390/polym13152510