Precursor-Directed Biosynthesis of Aminofulvenes: New Chalanilines from Endophytic Fungus Chalara sp.

The plant endophyte Chalara sp. is able to biotransform the epigenetic modifier vorinostat to form unique, aniline-containing polyketides named chalanilines. Here, we sought to expand the chemical diversity of chalaniline A-type molecules by changing the aniline moiety in the precursor vorinostat. I...

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Detalles Bibliográficos
Autores principales: Khoshbakht, Mahsa, Srey, Jason, Adpressa, Donovon A., Jagels, Annika, Loesgen, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347292/
https://www.ncbi.nlm.nih.gov/pubmed/34361574
http://dx.doi.org/10.3390/molecules26154418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347292/
https://www.ncbi.nlm.nih.gov/pubmed/34361574
http://dx.doi.org/10.3390/molecules26154418

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