CYPstrate: A Set of Machine Learning Models for the Accurate Classification of Cytochrome P450 Enzyme Substrates and Non-Substrates

The interaction of small organic molecules such as drugs, agrochemicals, and cosmetics with cytochrome P450 enzymes (CYPs) can lead to substantial changes in the bioavailability of active substances and hence consequences with respect to pharmacological efficacy and toxicity. Therefore, efficient me...

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Detalles Bibliográficos
Autores principales: Holmer, Malte, de Bruyn Kops, Christina, Stork, Conrad, Kirchmair, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347321/
https://www.ncbi.nlm.nih.gov/pubmed/34361831
http://dx.doi.org/10.3390/molecules26154678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347321/
https://www.ncbi.nlm.nih.gov/pubmed/34361831
http://dx.doi.org/10.3390/molecules26154678

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