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Mobility of Nucleostemin in Live Cells Is Specifically Related to Transcription Inhibition by Actinomycin D and GTP-Binding Motif

In vertebrates, nucleostemin (NS) is an important marker of proliferation in several types of stem and cancer cells, and it can also interact with the tumor-suppressing transcription factor p53. In the present study, the intra-nuclear diffusional dynamics of native NS tagged with GFP and two GFP-tag...

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Detalles Bibliográficos
Autores principales: Pack, Chan-Gi, Jung, Keehoon, Paulson, Bjorn, Kim, Jun Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347349/
https://www.ncbi.nlm.nih.gov/pubmed/34361059
http://dx.doi.org/10.3390/ijms22158293