Ligand-Dependent and Ligand-Independent Effects of Ephrin-B2–EphB4 Signaling in Melanoma Metastatic Spine Disease

Tumor–endothelial cell interactions represent an essential mechanism in spinal metastasis. Ephrin-B2–EphB4 communication induces tumor cell repulsion from the endothelium in metastatic melanoma, reducing spinal bone metastasis formation. To shed further light on the Ephrin-B2–EphB4 signaling mechani...

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Detalles Bibliográficos
Autores principales: Piffko, Andras, Broggini, Thomas, Harms, Christoph, Adams, Ralf Heinrich, Vajkoczy, Peter, Czabanka, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347368/
https://www.ncbi.nlm.nih.gov/pubmed/34360793
http://dx.doi.org/10.3390/ijms22158028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347368/
https://www.ncbi.nlm.nih.gov/pubmed/34360793
http://dx.doi.org/10.3390/ijms22158028

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