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Fedratinib Attenuates Bleomycin-Induced Pulmonary Fibrosis via the JAK2/STAT3 and TGF-β1 Signaling Pathway

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease with multiple causes, characterized by excessive myofibrocyte aggregation and extracellular matrix deposition. Related studies have shown that transforming growth factor-β1 (TGF-β1) is a key cytokine causing fibr...

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Detalles Bibliográficos
Autores principales: Ruan, Hao, Luan, Jiaoyan, Gao, Shaoyan, Li, Shuangling, Jiang, Qiuyan, Liu, Rui, Liang, Qing, Zhang, Ruiqin, Zhang, Fangxia, Li, Xiaohe, Zhou, Honggang, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347567/
https://www.ncbi.nlm.nih.gov/pubmed/34361644
http://dx.doi.org/10.3390/molecules26154491