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Identification of an IL-22-Dependent Gene Signature as a Pharmacodynamic Biomarker

Interleukin-22 (IL-22) plays a role in epithelial barrier function and repair, and may provide benefits in conditions like inflammatory bowel disease. However, limited human data are available to assess the clinical effect of IL-22 administration. This study used a human intestinal cell line to iden...

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Detalles Bibliográficos
Autores principales: Rae, Julie, Hackney, Jason, Huang, Kevin, Keir, Mary, Herman, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347589/
https://www.ncbi.nlm.nih.gov/pubmed/34360971
http://dx.doi.org/10.3390/ijms22158205