The Prion-Like Spreading of Alpha-Synuclein in Parkinson’s Disease: Update on Models and Hypotheses

The pathological aggregation of the presynaptic protein α-synuclein (α-syn) and propagation through synaptically coupled neuroanatomical tracts is increasingly thought to underlie the pathophysiological progression of Parkinson’s disease (PD) and related synucleinopathies. Although the precise molec...

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Detalles Bibliográficos
Autores principales: Jan, Asad, Gonçalves, Nádia Pereira, Vaegter, Christian Bjerggaard, Jensen, Poul Henning, Ferreira, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347623/
https://www.ncbi.nlm.nih.gov/pubmed/34361100
http://dx.doi.org/10.3390/ijms22158338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347623/
https://www.ncbi.nlm.nih.gov/pubmed/34361100
http://dx.doi.org/10.3390/ijms22158338

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