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HPMA-Based Polymer Conjugates for Repurposed Drug Mebendazole and Other Imidazole-Based Therapeutics

Recently, the antitumor potential of benzimidazole anthelmintics, such as mebendazole and its analogues, have been reported to have minimal side effects, in addition to their well-known anti-parasitic abilities. However, their administration is strongly limited owing to their extremely poor solubili...

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Detalles Bibliográficos
Autores principales: Studenovský, Martin, Rumlerová, Anna, Kostka, Libor, Etrych, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347626/
https://www.ncbi.nlm.nih.gov/pubmed/34372133
http://dx.doi.org/10.3390/polym13152530