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Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats

The aim of the present research was to describe the consequences of hyperlipidemia (HL) on the pharmacokinetics of glibenclamide (Gb) in poloxamer 407-induced hyperlipidemic rats. Rats were given intraperitoneal dose of poloxamer 407 to cause hyperlipidemia. A single oral dose of Gb (10 mg/Kg) was g...

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Detalles Bibliográficos
Autores principales: Bin Jardan, Yousef A., Ahad, Abdul, Raish, Mohammad, Ahmad, Ajaz, Alam, Mohd Aftab, Al-Mohizea, Abdullah M., Al-Jenoobi, Fahad I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347666/
https://www.ncbi.nlm.nih.gov/pubmed/34400867
http://dx.doi.org/10.1016/j.jsps.2021.05.002