mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics

The Hippo and mTOR signaling cascades are major regulators of cell growth and division. Aberrant regulation of these pathways has been demonstrated to contribute to gliomagenesis and result in enhanced glioblastoma proliferation and invasive characteristics. Several crosstalk mechanisms have been de...

Descripción completa

Detalles Bibliográficos
Autores principales: Holmes, Brent, Benavides-Serrato, Angelica, Saunders, Jacquelyn T., Kumar, Sunil, Nishimura, Robert N., Gera, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347669/
https://www.ncbi.nlm.nih.gov/pubmed/34343821
http://dx.doi.org/10.1016/j.neo.2021.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347669/
https://www.ncbi.nlm.nih.gov/pubmed/34343821
http://dx.doi.org/10.1016/j.neo.2021.07.005

Ejemplares similares