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mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics
The Hippo and mTOR signaling cascades are major regulators of cell growth and division. Aberrant regulation of these pathways has been demonstrated to contribute to gliomagenesis and result in enhanced glioblastoma proliferation and invasive characteristics. Several crosstalk mechanisms have been de...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347669/ https://www.ncbi.nlm.nih.gov/pubmed/34343821 http://dx.doi.org/10.1016/j.neo.2021.07.005 |