Catalytic Enantioselective Addition of Alkylzirconium Reagents to Aliphatic Aldehydes

A catalytic methodology for the enantioselective addition of alkylzirconium reagents to aliphatic aldehydes is reported here. The versatile and readily accessible chiral Ph-BINMOL ligand, in the presence of Ti(O(i)Pr)(4) and a zinc salt, facilitates the reaction, which proceeds under mild conditions...

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Detalles Bibliográficos
Autores principales: Vaccari, Jade, González-Soria, María José, Carter, Nicholas, Maciá, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347741/
https://www.ncbi.nlm.nih.gov/pubmed/34361623
http://dx.doi.org/10.3390/molecules26154471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347741/
https://www.ncbi.nlm.nih.gov/pubmed/34361623
http://dx.doi.org/10.3390/molecules26154471

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