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Mesenchymal Stem Cells Can Both Enhance and Inhibit the Cellular Response to DNA Immunization by Genes of Nonstructural Proteins of the Hepatitis C Virus

Despite extensive research, there is still no vaccine against the hepatitis C virus (HCV). The aim of this study was to investigate whether MSCs can exhibit adjuvant properties during DNA vaccination against hepatitis C. We used the pcNS3-NS5B plasmid encoding five nonstructural HCV proteins and MSC...

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Detalles Bibliográficos
Autores principales: Masalova, Olga V., Lesnova, Ekaterina I., Klimova, Regina R., Ivanov, Alexander V., Kushch, Alla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347804/
https://www.ncbi.nlm.nih.gov/pubmed/34360889
http://dx.doi.org/10.3390/ijms22158121