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Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment

Platinum-based chemotherapies, such as cisplatin, play a large role in cancer treatment. The development of resistance and treatment toxicity creates substantial barriers to disease control, yet. To enhance the therapeutic index of cisplatin-based chemotherapy, it is imperative to circumvent resista...

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Detalles Bibliográficos
Autores principales: Kiss, Robert Csaba, Xia, Fen, Acklin, Scarlett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347825/
https://www.ncbi.nlm.nih.gov/pubmed/34360968
http://dx.doi.org/10.3390/ijms22158199