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Development of a Bispecific Antibody-Based Platform for Retargeting of Capsid Modified AAV Vectors
A major limiting factor for systemically delivered gene therapies is the lack of novel tissue specific AAV (Adeno-associated virus) derived vectors. Bispecific antibodies can be used to redirect AAVs to specific target receptors. Here, we demonstrate that the insertion of a short linear epitope “2E3...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347852/ https://www.ncbi.nlm.nih.gov/pubmed/34361120 http://dx.doi.org/10.3390/ijms22158355 |