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Anti-Cancer Effects of Zotarolimus Combined with 5-Fluorouracil Treatment in HCT-116 Colorectal Cancer-Bearing BALB/c Nude Mice

Zotarolimus is a semi-synthetic derivative of rapamycin and an inhibitor of mammalian target of rapamycin (mTOR) signaling. Currently, zotarolimus is used to prolong the survival time of organ grafts, but it is also a novel immunosuppressive agent with potent anti-proliferative activity. Here, we ex...

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Detalles Bibliográficos
Autores principales: Chang, Geng-Ruei, Kuo, Chan-Yen, Tsai, Ming-Yang, Lin, Wei-Li, Lin, Tzu-Chun, Liao, Huei-Jyuan, Chen, Chung-Hung, Wang, Yu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347948/
https://www.ncbi.nlm.nih.gov/pubmed/34361836
http://dx.doi.org/10.3390/molecules26154683