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ADAM 17 and Epithelial-to-Mesenchymal Transition: The Evolving Story and Its Link to Fibrosis and Cancer

For decades, metalloproteinase 17 (ADAM17) has been the goal of wide investigation. Since its discovery as the tumour necrosis factor-α convertase, it has been studied as the main drug target, especially in the context of inflammatory conditions and tumour. In fact, evidence is mounting to support a...

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Detalles Bibliográficos
Autores principales: Sisto, Margherita, Ribatti, Domenico, Lisi, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347979/
https://www.ncbi.nlm.nih.gov/pubmed/34362154
http://dx.doi.org/10.3390/jcm10153373