Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes

IBMPFD/ALS is a genetic disorder caused by a single amino acid mutation on the p97 ATPase, promoting ATPase activity and cofactor dysregulation. The disease mechanism underlying p97 ATPase malfunction remains unclear. To understand how the mutation alters the ATPase regulation, we assembled a full-l...

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Detalles Bibliográficos
Autores principales: Nandi, Purbasha, Li, Shan, Columbres, Rod Carlo A., Wang, Feng, Williams, Dewight R., Poh, Yu-Ping, Chou, Tsui-Fen, Chiu, Po-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347982/
https://www.ncbi.nlm.nih.gov/pubmed/34360842
http://dx.doi.org/10.3390/ijms22158079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347982/
https://www.ncbi.nlm.nih.gov/pubmed/34360842
http://dx.doi.org/10.3390/ijms22158079

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