Sex-Based Impact of Creatine Supplementation on Depressive Symptoms, Brain Serotonin and SSRI Efficacy in an Animal Model of Treatment-Resistant Depression

Background: Rates of major depressive disorder (MDD) increase with living at altitude. In our model, rats housed at moderate altitude (in hypobaric hypoxia) exhibit increased depression-like behavior, altered brain serotonin and a lack of antidepressant response to most selective serotonin reuptake...

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Detalles Bibliográficos
Autores principales: Kanekar, Shami, Ettaro, Robert, Hoffman, Michael D., Ombach, Hendrik J., Brown, Jadeda, Lynch, Cayla, Sheth, Chandni S., Renshaw, Perry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348220/
https://www.ncbi.nlm.nih.gov/pubmed/34360959
http://dx.doi.org/10.3390/ijms22158195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348220/
https://www.ncbi.nlm.nih.gov/pubmed/34360959
http://dx.doi.org/10.3390/ijms22158195

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