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PON-Sol2: Prediction of Effects of Variants on Protein Solubility

Genetic variations have a multitude of effects on proteins. A substantial number of variations affect protein–solvent interactions, either aggregation or solubility. Aggregation is often related to structural alterations, whereas solubilizable proteins in the solid phase can be made again soluble by...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Zeng, Lianjie, Vihinen, Mauno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348231/
https://www.ncbi.nlm.nih.gov/pubmed/34360790
http://dx.doi.org/10.3390/ijms22158027