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Prediction of Drug-Induced Liver Toxicity Using SVM and Optimal Descriptor Sets

Drug-induced liver toxicity is one of the significant safety challenges for the patient’s health and the pharmaceutical industry. It causes termination of drug candidates in clinical trials and also the retractions of approved drugs from the market. Thus, it is essential to identify hepatotoxic comp...

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Detalles Bibliográficos
Autores principales: Jaganathan, Keerthana, Tayara, Hilal, Chong, Kil To
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348336/
https://www.ncbi.nlm.nih.gov/pubmed/34360838
http://dx.doi.org/10.3390/ijms22158073