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T-2 Toxin Induces Oxidative Stress at Low Doses via Atf3ΔZip2a/2b-Mediated Ubiquitination and Degradation of Nrf2

T-2 toxin is mainly produced by Fusarium species, which is an extremely toxic mycotoxin to humans and animals. It is well known that T-2 toxin induces oxidative stress, but the molecular mechanism is still unknown. In this study, we found that T-2 toxin significantly promoted reactive oxygen species...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoxuan, Mu, Peiqiang, Zhu, Lang, Mao, Xiaoxiao, Chen, Shuang, Zhong, Huali, Deng, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348355/
https://www.ncbi.nlm.nih.gov/pubmed/34360702
http://dx.doi.org/10.3390/ijms22157936