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Strategies and Approaches for Discovery of Small Molecule Disruptors of Biofilm Physiology

Biofilms, the predominant growth mode of microorganisms, pose a significant risk to human health. The protective biofilm matrix, typically composed of exopolysaccharides, proteins, nucleic acids, and lipids, combined with biofilm-grown bacteria’s heterogenous physiology, leads to enhanced fitness an...

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Detalles Bibliográficos
Autores principales: Trebino, Michael A., Shingare, Rahul D., MacMillan, John B., Yildiz, Fitnat H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348372/
https://www.ncbi.nlm.nih.gov/pubmed/34361735
http://dx.doi.org/10.3390/molecules26154582