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Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α-Glucosidase Inhibitor

α-glucosidase is a major enzyme that is involved in starch digestion and type 2 diabetes mellitus. In this study, the inhibition of hypericin by α-glucosidase and its mechanism were firstly investigated using enzyme kinetics analysis, real-time interaction analysis between hypericin and α-glucosidas...

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Detalles Bibliográficos
Autores principales: Dong, Qi, Hu, Na, Yue, Huilan, Wang, Honglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348433/
https://www.ncbi.nlm.nih.gov/pubmed/34361714
http://dx.doi.org/10.3390/molecules26154566