A Potent Leukocyte Transmigration Blocker: GT-73 Showed a Protective Effect against LPS-Induced ARDS in Mice

We recently developed a molecule (GT-73) that blocked leukocyte transendothelial migration from blood to the peripheral tissues, supposedly by affecting the platelet endothelial cell adhesion molecule (PECAM-1) function. GT-73 was tested in an LPS-induced acute respiratory distress syndrome (ARDS) m...

Descripción completa

Detalles Bibliográficos
Autores principales: Blum, Eliav, Margalit, Raanan, Levy, Laura, Getter, Tamar, Lahav, Ron, Zilber, Sofia, Bradfield, Paul, Imhof, Beat A., Alpert, Evgenia, Gruzman, Arie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348436/
https://www.ncbi.nlm.nih.gov/pubmed/34361736
http://dx.doi.org/10.3390/molecules26154583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348436/
https://www.ncbi.nlm.nih.gov/pubmed/34361736
http://dx.doi.org/10.3390/molecules26154583

Ejemplares similares