Cargando…

A Potent Leukocyte Transmigration Blocker: GT-73 Showed a Protective Effect against LPS-Induced ARDS in Mice

We recently developed a molecule (GT-73) that blocked leukocyte transendothelial migration from blood to the peripheral tissues, supposedly by affecting the platelet endothelial cell adhesion molecule (PECAM-1) function. GT-73 was tested in an LPS-induced acute respiratory distress syndrome (ARDS) m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blum, Eliav, Margalit, Raanan, Levy, Laura, Getter, Tamar, Lahav, Ron, Zilber, Sofia, Bradfield, Paul, Imhof, Beat A., Alpert, Evgenia, Gruzman, Arie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348436/ https://www.ncbi.nlm.nih.gov/pubmed/34361736 http://dx.doi.org/10.3390/molecules26154583

Ejemplares similares

A Role for the αvβ3 Integrin in the Transmigration of Monocytes
por: Weerasinghe, Dheepika, et al.
Publicado: (1998)

The Effect of a G:T Mispair on the Dynamics of DNA
por: Imhof, Petra, et al.
Publicado: (2013)

Efficacy and Safety of Elbasvir/Grazoprevir in Hepatitis C Virus GT1- and GT4-Infected People Aged 65 Years or Older
por: Flamm, Steven, et al.
Publicado: (2019)

Beta-Blockers in COVID-ARDS: Inflammation or Hemodynamic?
por: de Roquetaillade, Charles, et al.
Publicado: (2022)

Transmigration of ingested asbestos.
por: Meek, M E
Publicado: (1983)

Transmigration of Mandibular Canines
por: Umashree, N., et al.
Publicado: (2013)

The Natural Protective Mechanism Against Hyperglycemia in Vascular Endothelial Cells: Roles of the Lipid Peroxidation Product 4-Hydroxydodecadienal and Peroxisome Proliferator–Activated Receptor δ
por: Riahi, Yael, et al.
Publicado: (2010)

Neuromuscular blockers and ARDS: Thou shalt not breathe, move, or die!
por: Yegneswaran, Balaji, et al.
Publicado: (2011)

Endothelial Transmigration by Trypanosoma cruzi
por: Coates, Bria M., et al.
Publicado: (2013)

Investigation of transmigrated mandibular canines
por: Azeem, Muhammad, et al.
Publicado: (2019)

Unusual intraosseous transmigration of impacted tooth
por: Kumar, Santosh, et al.
Publicado: (2012)

Management of a transmigrated mandibular canine
por: Verma, Sneh Lata, et al.
Publicado: (2012)

Transmigration of mandibular canine – case report
por: Gruszka, Katarzyna, et al.
Publicado: (2014)

When Echinococcus granulosus transmigrates from the liver into the pericardium: a case report
por: Kuemmerli, Christoph, et al.
Publicado: (2021)

Age-dependent development of liver fibrosis in Glmp(gt/gt) mice
por: Nesset, Cecilie K., et al.
Publicado: (2016)

Statement complementing the EFSA Scientific Opinion on application (EFSA‐GMO‐NL‐2009‐75) for placing on the market of genetically modified oilseed rape Ms8 × Rf3 × GT73 and subcombinations, which have not been authorised previously (i.e. Ms8 × GT73 and Rf3 × GT73) independently of their origin, for food and feed uses, import and processing, with the exception of isolated seed protein for food, under Regulation (EC) No 1829/2003), taking into consideration additional information
por: Naegeli, Hanspeter, et al.
Publicado: (2020)

Search for the Higgs boson in the H ->WW->lvlv channel in ATLAS
por: Armbruster, A
Publicado: (2011)

A Study of Transmigrated Canine in an Indian Population
por: Sharma, Gaurav, et al.
Publicado: (2014)

Transmigration or Epidermization of Lip: Does an Entity Exist?
por: Neema, Shekhar, et al.
Publicado: (2020)

Endothelial Barrier Function and Leukocyte Transmigration in Atherosclerosis
por: Sluiter, Thijs J., et al.
Publicado: (2021)

Homeland Run: Israeli Baseball and American Transmigrants
por: Segal, Amir
Publicado: (2023)

H->tau tau and H->tau nu with the ATLAS Detector at the LHC
por: Goncalo, R
Publicado: (2011)

Study of H(SUSY) -> Tautau -> l + Tau Jet + Etmis in CMS
por: Kinnunen, Ritva, et al.
Publicado: (1997)

Solar origin of Major GMSs with (-50nT>Dst>-100nT)
por: Kaur, S
Publicado: (2005)

Net widens for funding of <i>arXiv</i>
Publicado: (2010)

Search for the SM Higgs Boson in H->WW->lnu lnu with ATLAS
por: Schmidt, E
Publicado: (2012)

Monitoring lung injury with particle flow rate in LPS‐ and COVID‐19‐induced ARDS
por: Stenlo, Martin, et al.
Publicado: (2021)

Assessment of genetically modified oilseed rape GT73 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐002)
por: Naegeli, Hanspeter, et al.
Publicado: (2020)

Expression of the Gene for Autotransporter AutB of Neisseria meningitidis Affects Biofilm Formation and Epithelial Transmigration
por: Arenas, Jesús, et al.
Publicado: (2016)

Spitzenforschung im Kleinformat >
Publicado: (2009)

Breakdown of the Endothelial Barrier Function in Tumor Cell Transmigration
por: Mierke, Claudia Tanja, et al.
Publicado: (2008)

Initial steps of metastasis: Cell invasion and endothelial transmigration
por: van Zijl, Franziska, et al.
Publicado: (2011)

Differentiation and Transmigration of CD4 T Cells in Neuroinflammation and Autoimmunity
por: Sonar, Sandip Ashok, et al.
Publicado: (2017)

Canine transmigration accompanying mandibular retrognathism secondary to osteitis
por: Koszowski, Rafał, et al.
Publicado: (2015)

Piezosurgery-Assisted Surgical Treatment in Impacted Canine Transmigration
por: Rodrigues, Matheus Francisco Barros, et al.
Publicado: (2020)

Inhibitors of Human Neuraminidase Enzymes Block Transmigration in vitro
por: Howlader, Md. Amran, et al.
Publicado: (2022)

Multifunctionality of prostatic acid phosphatase in prostate cancer pathogenesis
por: Alpert, Evgenia, et al.
Publicado: (2021)

First Observation of the process Z -> tautau -> emu + 4nu with the ATLAS Detector
por: The ATLAS collaboration
Publicado: (2011)

Search for the Higgs boson in the H->WW->lnln decay mode with the ATLAS Detector
por: The ATLAS collaboration
Publicado: (2011)

Data Driven W+jets background estimation for H->WW->llvv(Higgs)
por: Asfandiyarov, R
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_r2poooale3gn1nh10gnorbfa2q