Leukemia-Induced Cellular Senescence and Stemness Alterations in Mesenchymal Stem Cells Are Reversible upon Withdrawal of B-Cell Acute Lymphoblastic Leukemia Cells

Leukemic cell growth in the bone marrow (BM) induces a very stressful condition. Mesenchymal stem cells (MSC), a key component of this BM niche, are affected in several ways with unfavorable consequences on hematopoietic stem cells favoring leukemic cells. These alterations in MSC during B-cell acut...

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Detalles Bibliográficos
Autores principales: Vanegas, Natalia-Del Pilar, Ruiz-Aparicio, Paola Fernanda, Uribe, Gloria Inés, Linares-Ballesteros, Adriana, Vernot, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348535/
https://www.ncbi.nlm.nih.gov/pubmed/34360930
http://dx.doi.org/10.3390/ijms22158166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348535/
https://www.ncbi.nlm.nih.gov/pubmed/34360930
http://dx.doi.org/10.3390/ijms22158166

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