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Caveolin-1 Expression in the Dorsal Striatum Drives Methamphetamine Addiction-Like Behavior

Dopamine D1 receptor (D1R) function is regulated by membrane/lipid raft-resident protein caveolin-1 (Cav1). We examined whether altered expression of Cav1 in the dorsal striatum would affect self-administration of methamphetamine, an indirect agonist at the D1Rs. A lentiviral construct expressing Ca...

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Detalles Bibliográficos
Autores principales: Avchalumov, Yosef, Kreisler, Alison D., Trenet, Wulfran, Nayak, Mahasweta, Head, Brian P., Piña-Crespo, Juan C., Mandyam, Chitra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348638/
https://www.ncbi.nlm.nih.gov/pubmed/34360984
http://dx.doi.org/10.3390/ijms22158219