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Colorectal Cancer Apoptosis Induced by Dietary δ-Valerobetaine Involves PINK1/Parkin Dependent-Mitophagy and SIRT3

Understanding the mechanisms of colorectal cancer progression is crucial in the setting of strategies for its prevention. δ-Valerobetaine (δVB) is an emerging dietary metabolite showing cytotoxic activity in colon cancer cells via autophagy and apoptosis. Here, we aimed to deepen current knowledge o...

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Detalles Bibliográficos
Autores principales: D’Onofrio, Nunzia, Martino, Elisa, Mele, Luigi, Colloca, Antonino, Maione, Martina, Cautela, Domenico, Castaldo, Domenico, Balestrieri, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348679/
https://www.ncbi.nlm.nih.gov/pubmed/34360883
http://dx.doi.org/10.3390/ijms22158117