Preparation and Evaluation of Novel Folate Isonitrile (99m)Tc Complexes as Potential Tumor Imaging Agents to Target Folate Receptors

In order to seek novel technetium-99m folate receptor-targeting agents, two folate derivatives (CN5FA and CNPFA) were synthesized and radiolabeled to obtain [(99m)Tc]Tc-CN5FA and [(99m)Tc]Tc-CNPFA complexes, which exhibited high radiochemical purity (>95%) without purification, hydrophilicity, an...

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Detalles Bibliográficos
Autores principales: Feng, Junhong, Zhang, Xuran, Ruan, Qing, Jiang, Yuhao, Zhang, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348780/
https://www.ncbi.nlm.nih.gov/pubmed/34361705
http://dx.doi.org/10.3390/molecules26154552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348780/
https://www.ncbi.nlm.nih.gov/pubmed/34361705
http://dx.doi.org/10.3390/molecules26154552

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