Cargando…

Preparation and Evaluation of Novel Folate Isonitrile (99m)Tc Complexes as Potential Tumor Imaging Agents to Target Folate Receptors

In order to seek novel technetium-99m folate receptor-targeting agents, two folate derivatives (CN5FA and CNPFA) were synthesized and radiolabeled to obtain [(99m)Tc]Tc-CN5FA and [(99m)Tc]Tc-CNPFA complexes, which exhibited high radiochemical purity (>95%) without purification, hydrophilicity, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Junhong, Zhang, Xuran, Ruan, Qing, Jiang, Yuhao, Zhang, Junbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348780/ https://www.ncbi.nlm.nih.gov/pubmed/34361705 http://dx.doi.org/10.3390/molecules26154552

Ejemplares similares

Synthesis and Evaluation of Novel Norfloxacin Isonitrile (99m)Tc Complexes as Potential Bacterial Infection Imaging Agents
por: Fang, Si’an, et al.
Publicado: (2021)

Preparation and Bioevaluation of a Novel (99m)Tc-Labeled Glucose Derivative Containing Cyclohexane as a Promising Tumor Imaging Agent
por: Feng, Junhong, et al.
Publicado: (2023)

Preparation and Bioevaluation of Novel (99m)Tc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia
por: Ruan, Qing, et al.
Publicado: (2021)

Evaluation of (99m)Tc-CN5DG as a broad-spectrum SPECT probe for tumor imaging
por: Zhang, Xuran, et al.
Publicado: (2020)

Radiolabeling and Biological Evaluation of Novel (99m)Tc-Nitrido and (99m)Tc-Oxo Complexes with 4-Methoxy-(L)-Phenylalanine Dithiocarbamate for Tumor Imaging
por: Yin, Guangxing, et al.
Publicado: (2022)

Design, Preparation, and Evaluation of a Novel (99m)TcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent
por: Fang, Si’an, et al.
Publicado: (2020)

Preparation and Biological Evaluation of [(99m)Tc]Tc-CNGU as a PSMA-Targeted Radiotracer for the Imaging of Prostate Cancer
por: Xiao, Di, et al.
Publicado: (2020)

The synthesis of a (99m)Tc-labeled tetravalent targeting probe upon isonitrile coordination to (99m)Tc(I) for enhanced target uptake in saturable systems
por: Mizuno, Yuki, et al.
Publicado: (2019)

Diagnostic Performances of 99mTc-Methoxy Isobutyl Isonitrile Scan in Predicting the Malignancy of Lung Lesions: A Meta-Analysis
por: Zhang, Shuxin, et al.
Publicado: (2016)

Synthesis and Evaluation of (99m)Tc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging
por: Ruan, Qing, et al.
Publicado: (2023)

The Use of (99m)Tc-Methoxy-isobutyl-isonitrile (sestaMIBI) Uptake on Scintigraphy ((99m)-STS) in Amiodarone-Induced Thyrotoxicosis: Case Series and Review of the Literature
por: Elshimy, Ghada, et al.
Publicado: (2020)

Effect of paternal folate deficiency on placental folate content and folate receptor α expression in rats
por: Kim, Hye Won, et al.
Publicado: (2011)

Giant cystic parathyroid adenoma with thrombosis of internal jugular vein seen on CT and Tc-99m methoxy isobutyl isonitrile parathyroid scan
por: Zaman, Maseeh uz, et al.
Publicado: (2012)

Diagnostic Performance of (99m)Tc-Methoxy-Isobuty-Isonitrile (MIBI) for Risk Stratification of Hypofunctioning Thyroid Nodules: A European Multicenter Study
por: Schenke, Simone Agnes, et al.
Publicado: (2022)

Use of (99m)Tc 2-methoxyisobutyl isonitrile in minimally invasive radioguided surgery in patients with primary hyperparathyroidism: A narrative review of the current literature
por: Denmeade, Kristie A, et al.
Publicado: (2013)

Preparation of (99m)Tc-PQQ and preliminary biological evaluation for the NMDA receptor
por: Kong, Yanyan, et al.
Publicado: (2010)

New (55)Co-labeled Albumin-Binding Folate Derivatives as Potential PET Agents for Folate Receptor Imaging
por: Radford, Lauren L., et al.
Publicado: (2019)

Brain Uptake of Folate Forms in the Presence of Folate Receptor Alpha Antibodies in Young Rats: Folate and Antibody Distribution
por: Bobrowski-Khoury, Natasha, et al.
Publicado: (2023)

Expression of folate receptors in nasopharyngeal and laryngeal carcinoma and folate receptor-mediated endocytosis by molecular targeted nanomedicine
por: Xie, M, et al.
Publicado: (2013)

(99m)Tc-Radiolabeled TPGS Nanomicelles Outperform (99m)Tc-Sestamibi as Breast Cancer Imaging Agent
por: Tesan, Fiorella C., et al.
Publicado: (2019)

Folate receptor-targeted near-infrared photodynamic therapy for folate receptor-overexpressing tumors
por: Aung, Winn, et al.
Publicado: (2022)

Targeting folate receptor β positive tumor-associated macrophages in lung cancer with a folate-modified liposomal complex
por: Tie, Yan, et al.
Publicado: (2020)

Microbial Metabolic Capacity for Intestinal Folate Production and Modulation of Host Folate Receptors
por: Engevik, Melinda A., et al.
Publicado: (2019)

Synthesis of folate-chitosan nanoparticles loaded with ligustrazine to target folate receptor positive cancer cells
por: Cheng, Lichun, et al.
Publicado: (2017)

Preparation of (99m)Tc-Clomiphene Citrate as a Novel Agent for Breast Cancer Imaging
por: Ibrahim, Ismail Taha, et al.
Publicado: (2012)

Study of Binding Kinetics and Specificity of (99m)Tc-SSS-Complex and (99m)Tc-HMPAO to Blood Cells
por: Auletta, S., et al.
Publicado: (2018)

Preparation and Study of Folate Modified Albumin Targeting Microspheres
por: Zha, Quanbin, et al.
Publicado: (2022)

Functional coating of liposomes using a folate– polymer conjugate to target folate receptors
por: Watanabe, Kazuo, et al.
Publicado: (2012)

Preparation and Preliminary Biological Evaluation of Novel (99m)Tc-Labelled Thymidine Analogs as Tumor Imaging Agents
por: Lu, Chunxiong, et al.
Publicado: (2012)

Comparison of [(99m)Tc]Tc-tilmanocept with [(99m)Tc]Tc-sulphur colloids and [(99m)Tc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head
por: Ooms, Mark, et al.
Publicado: (2022)

Folate in pregnancy
por: Chidambaram, Balasubramaniam
Publicado: (2012)

Folate Receptor Targeted Imaging Using Poly (ethylene glycol)-folate: In Vitro and In Vivo Studies
por: Kim, Se-Lim, et al.
Publicado: (2007)

Preparation and Crystal Structure of a Rhenium Analogue of the Cationic Renal Agent, Tc-99m Diaminocyclohexane
por: Marzilli, Luigi G., et al.
Publicado: (2000)

Convergence pattern studies of folate receptor
por: Ramamoorthy, Kalidoss, et al.
Publicado: (2008)

(99m)Tc-LHRH in tumor receptor imaging
por: Hao, Dawei, et al.
Publicado: (2017)

Clinical usefulness of (99m)Tc-HYNIC-TOC, (99m)Tc(V)-DMSA, and (99m)Tc-MIBI SPECT in the evaluation of pituitary adenomas
por: Vukomanovic, Vladimir R., et al.
Publicado: (2019)

Synthesis and Characterization of Bidentate Isonitrile Iron Complexes
por: Till, Marion, et al.
Publicado: (2021)

The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway
Publicado: (1990)

Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size
por: Meredith, Megan, et al.
Publicado: (2016)

Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging
por: De Jesus, Elizabeth, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_i4fhfg1lmvhes887uisaitlkf8