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Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis

BACKGROUND: Sarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Therefore, genetic and/or epigenetic changes profoundly affect the biology of sarcoma...

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Detalles Bibliográficos
Autores principales: Jimenez-García, Manuel Pedro, Lucena-Cacace, Antonio, Otero-Albiol, Daniel, Carnero, Amancio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348834/
https://www.ncbi.nlm.nih.gov/pubmed/34364391
http://dx.doi.org/10.1186/s13046-021-02048-9