Cargando…

Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis

BACKGROUND: Sarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Therefore, genetic and/or epigenetic changes profoundly affect the biology of sarcoma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jimenez-García, Manuel Pedro, Lucena-Cacace, Antonio, Otero-Albiol, Daniel, Carnero, Amancio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348834/ https://www.ncbi.nlm.nih.gov/pubmed/34364391 http://dx.doi.org/10.1186/s13046-021-02048-9

Ejemplares similares

Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2
por: Jimenez-García, Manuel Pedro, et al.
Publicado: (2021)

Empty Spiracles Homeobox 2 (EMX2) Inhibits the Invasion and Tumorigenesis in Colorectal Cancer Cells
por: Zhang, Yan, et al.
Publicado: (2017)

Binding of microRNA-135a (miR-135a) to homeobox protein A10 (HOXA10) mRNA in a high-progesterone environment modulates the embryonic implantation factors beta3-integrin (ITGβ3) and empty spiracles homeobox-2 (EMX2)
por: Luo, Xi, et al.
Publicado: (2021)

Emx1 Is Required for Neocortical Area Patterning
por: Stocker, Adam M., et al.
Publicado: (2016)

Emx2 as a novel tool to suppress glioblastoma
por: Falcone, Carmen, et al.
Publicado: (2016)

DNA methylation-activated full-length EMX1 facilitates metastasis through EMX1-EGFR-ERK axis in hepatocellular carcinoma
por: Wen, Dong-sheng, et al.
Publicado: (2023)

Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter
por: Beckmann, Jan, et al.
Publicado: (2011)

Deciphering the Role of Emx1 in Neurogenesis: A Neuroproteomics Approach
por: Kobeissy, Firas H., et al.
Publicado: (2016)

NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis
por: Lucena-Cacace, Antonio, et al.
Publicado: (2017)

Emx2 and early hair cell development in the mouse inner ear
por: Holley, Matthew, et al.
Publicado: (2010)

Tuning of neocortical astrogenesis rates by Emx2 in neural stem cells
por: Falcone, Carmen, et al.
Publicado: (2015)

Homeogene emx1 is required for nephron distal segment development in zebrafish
por: Morales, Elvin E., et al.
Publicado: (2018)

Drosophila Homeodomain-Interacting Protein Kinase (Hipk) Phosphorylates the Homeodomain Proteins Homeobrain, Empty Spiracles, and Muscle Segment Homeobox
por: Steinmetz, Eva Louise, et al.
Publicado: (2019)

Adenoviral Delivery of the EMX2 Gene Suppresses Growth in Human Gastric Cancer
por: Li, Jie, et al.
Publicado: (2012)

Regulation of Emx2 Expression by Antisense Transcripts in Murine Cortico-Cerebral Precursors
por: Spigoni, Giulia, et al.
Publicado: (2010)

The expression of EMX2 lead to cell cycle arrest in glioblastoma cell line
por: Monnier, Annabelle, et al.
Publicado: (2018)

EMX2 gene expression predicts liver metastasis and survival in colorectal cancer
por: Aykut, Berk, et al.
Publicado: (2017)

Emx2 regulates hair cell rearrangement but not positional identity within neuromasts
por: Ohta, Sho, et al.
Publicado: (2020)

Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2
por: Ji, Young Rae, et al.
Publicado: (2022)

Genetic interplay between the transcription factors Sp8 and Emx2 in the patterning of the forebrain
por: Zembrzycki, Andreas, et al.
Publicado: (2007)

Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers
por: Mariani, J., et al.
Publicado: (2012)

EMX2 Is a Predictive Marker for Adjuvant Chemotherapy in Lung Squamous Cell Carcinomas
por: Yue, Dongsheng, et al.
Publicado: (2015)

Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells
por: Jiang, Tao, et al.
Publicado: (2017)

Emx1-Cre Is Expressed in Peripheral Autonomic Ganglia That Regulate Central Cardiorespiratory Functions
por: Ning, Yao, et al.
Publicado: (2022)

Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex
por: Chou, Shen-Ju, et al.
Publicado: (2009)

Directional selectivity of afferent neurons in zebrafish neuromasts is regulated by Emx2 in presynaptic hair cells
por: Ji, Young Rae, et al.
Publicado: (2018)

EMX2OS plays a prognosis-associated enhancer RNA role in gastric cancer
por: Liu, Ge-Xin, et al.
Publicado: (2021)

Vesicoureteral Reflux and Other Urinary Tract Malformations in Mice Compound Heterozygous for Pax2 and Emx2
por: Boualia, Sami K., et al.
Publicado: (2011)

Conserved roles of ems/Emx and otd/Otx genes in olfactory and visual system development in Drosophila and mouse
por: Sen, Sonia, et al.
Publicado: (2013)

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia
por: Kindt, Katie S., et al.
Publicado: (2021)

“SIT” with Emx1‐NuTRAP Mice: Simultaneous INTACT and TRAP for Paired Transcriptomic and Epigenetic Sequencing
por: Raus, Anthony M., et al.
Publicado: (2022)

EMX1 functions as a tumor inhibitor in spinal cord glioma through transcriptional suppression of WASF2 and inactivation of the Wnt/β‐catenin axis
por: Han, Ziyin, et al.
Publicado: (2022)

Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2
por: Tona, Yosuke, et al.
Publicado: (2020)

Downregulation of enhancer RNA EMX2OS is associated with poor prognosis in kidney renal clear cell carcinoma
por: Jiang, Huiming, et al.
Publicado: (2020)

Integrin β3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice
por: Lopuch, Andrew J., et al.
Publicado: (2022)

Reevaluating Emx gene phylogeny: homopolymeric amino acid tracts as a potential factor obscuring orthology signals in cyclostome genes
por: Noro, Miyuki, et al.
Publicado: (2015)

An Association between EMX2 Variations and Mayer-Rokitansky-Küster-Hauser Syndrome: A Case-Control Study of Chinese Women
por: Li, Haiping, et al.
Publicado: (2022)

The function of lncRNA EMX2OS/miR-653-5p and its regulatory mechanism in lung adenocarcinoma
por: Ma, Lina, et al.
Publicado: (2023)

Snail1 Expression Is Required for Sarcomagenesis()()
por: Alba-Castellón, Lorena, et al.
Publicado: (2014)

The downregulation of lncRNA EMX2OS might independently predict shorter recurrence-free survival of classical papillary thyroid cancer
por: Gu, Yi, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cqk33up0rusrhhpdnm8altf1j4