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DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice

BACKGROUND: Peroxisome proliferator-activated receptor alpha (PPARα) is associated with diabetic retinopathy (DR), and the underlying mechanism is still unclear. Aim of this work was to investigate the mechanism of PPARα in DR. METHODS: Human retinal capillary pericytes (HRCPs) were treated with hig...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Wang, Xinru, Zhou, Xiaoyun, Ding, Lexi, Liu, Dan, Xu, Huizhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348846/
https://www.ncbi.nlm.nih.gov/pubmed/34362460
http://dx.doi.org/10.1186/s40659-021-00347-1