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Distinct Immune Signatures Indicative of Treatment Response and Immune-Related Adverse Events in Melanoma Patients under Immune Checkpoint Inhibitor Therapy

To identify potential early biomarkers of treatment response and immune-related adverse events (irAE), a pilot immune monitoring study was performed in stage IV melanoma patients by flow cytometric analysis of peripheral blood mononuclear cells (PBMC). Overall, 17 patients were treated with either n...

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Detalles Bibliográficos
Autores principales: Reschke, Robin, Gussek, Philipp, Boldt, Andreas, Sack, Ulrich, Köhl, Ulrike, Lordick, Florian, Gora, Thomas, Kreuz, Markus, Reiche, Kristin, Simon, Jan-Christoph, Ziemer, Mirjana, Kunz, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8348898/
https://www.ncbi.nlm.nih.gov/pubmed/34360781
http://dx.doi.org/10.3390/ijms22158017